| Schauspieler | Rolle | Synchronsprecher | ||
| Dustin Hoffman Dustin Hoffman | Mr. Edward Magorium | Joachim Kerzel Joachim Kerzel | ||
| Natalie Portman Natalie Portman | Molly Mahoney | Manja Doering Manja Doering | ||
| Dash Grundy | Ari | Leonard Walenta | ||
| Samantha Harvey | Cassie | Selma Sarstedt | ||
| Mike Realba | Dave Wolf | Marius Clarén Marius Clarén | ||
| Jesse Bostick | Derek | Hariton Triandafilidis | ||
| Jonathan Potts | Dr. Dunn | Lutz Schnell Lutz Schnell | ||
| Matt Baram | Eddie, der Zahnarzt | Kim Hasper Kim Hasper | ||
| Rebecca Northan | Ellie Applebaum | Christin Marquitan Christin Marquitan | ||
| Zach Mills | Eric Applebaum | Leo Vornberger | ||
| Jason Bateman Jason Bateman | Henry Weston | Wolfgang Wagner | ||
| Oliver Masuda | Jordan | Johannes Walenta | ||
| Erica Jones | Kleines Mädchen | Carmen Pilz | ||
| Daniella Tokic | Krankenschwester | Almut Zydra Almut Zydra | ||
| Marcia Bennett | Lora | Margot Rothweiler Margot Rothweiler | ||
| Beatriz Yuste | Lora | Denise Gorzelanny | ||
| Brea Maloney | Mädchen #3 | Lisa Marie Prinz | ||
| Jade Cohen | Mädchen mit Känguruh | Carmen Pilz | ||
| Kiele Sanchez | Mrs. Goodman | Claudia Urbschat Mingues Claudia Urbschat Mingues | ||
| David Rendall | Tim | Nicholas Böge | ||
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